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CONTRAVE® (NALTREXONE AND BUPROPION)
CONTRAVE® (NALTREXONE AND BUPROPION)
CONTRAVE® (NALTREXONE AND BUPROPION)
CONTRAVE® combines low dose naltrexone, a medication commonly used to manage alcohol and opiod dependency, and Bupropion, an atypical antidepressant that is also prescribed for smoking cessation These medicines work on two separate areas of the brain that are involved in controlling eating (hunger and cravings). CONTRIVE® is delivered in the form of an oral tablet; at the maximum recommended dose of 2 tablets twice daily. In Canada it is approved for use (alongside a reduced calorie diet and increased physical activity) in adult patient with
- A body mass index (MVI) of 30kg/M2 or higher or
- A BMI of 27 KG/M2 or above with the presence of at least one weight-related condition such as Hypertension, Type 2 Diabetes or Dyslipidemia.
SAXENDA® (LIRAGLUTIDE)
CONTRAVE® (NALTREXONE AND BUPROPION)
CONTRAVE® (NALTREXONE AND BUPROPION)
GLP-1 (or glucagon-like peptide-1) is a hormone that is found naturally in your body that has effects on appetite and food intake. Saxenda® is a GLP-1 therapy that is similar to the natural GLP-1 found in your body. Saxenda® is thought to help patients lose weight by decreasing appetite and the amount you eat. Studies with Saxenda® have also shown that it may also improve other health factors beyond weight, including waist circumference, blood sugar, blood pressure and cholesterol levels. Saxenda® comes in a prefilled pen that you can use to self-inject.In Canada, Saxenda® is indicated along with a reduced-calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of:
- 30 kg/m2 or greater, or
- 27 kg/m2 or greater in the presence of at least one weight-related comorbidity (e.g., hypertension, type 2 diabetes or dyslipidemia) and who have failed a previous weight management intervention.
Wegovy
XENICAL® (ORLISTAT)
XENICAL® (ORLISTAT)
Wegovy™ (semaglutide) injection 2.4 mg is an injectable prescription medicine used for adults with obesity (BMI ≥30) or overweight (excess weight) (BMI ≥27) who also have weight-related medical problems to help them lose weight and keep the weight off.
Wegovy™ should be used with a reduced calorie meal plan and increased physical activity. Wegovy™ contains semaglutide and should not be used with other semaglutide-containing products or other GLP-1 receptor agonist medicines.
XENICAL® (ORLISTAT)
XENICAL® (ORLISTAT)
XENICAL® (ORLISTAT)
In order for fats from foods you eat to be absorbed into the body, they need to be broken down by enzymes called lipases.
When Xenical® is taken with meals, it prevents these enzymes from working and causes a decrease in the amount of fat your body absorbs from your food. When you absorb less fat, you take in fewer calories, leading to weight loss.
Xenical® does not decrease or change your appetite. Studies with Xenical® have also shown that it may also improve other health factors beyond weight, including waist circumference, blood sugar, blood pressure and cholesterol levels. Xenical® is administered as a capsule during or just following each main meal.
Bariatric Surgery
Weight loss surgery changes the way your digestive system works by closing off parts of the stomach. Making the stomach smaller means that you feel full after eating a small amount of food. Operations that reduce stomach size are known as restrictive operations because they restrict the amount of food the stomach can hold. Some operations combine restriction with a partial bypass of the small intestine (the intestines are where food and nutrients are absorbed into the body). By creating a detour around part of the intestine, less food is absorbed. Operations that use this mechanism to enhance weight loss are called malabsorptive operations. There are a number of different restrictive and malabsorptive operations being done. Here at Capital Health, we are doing a restrictive procedure called the “sleeve gastrectomy”, also called the gastric sleeve resection. Other types of weight loss surgeries are not done here. These include the laparoscopic adjustable gastric band procedure (LAGB) (stomach band, a restrictive operation), the Roux-en Y gastric bypass, the biliopancreatic diversion (a malabsorptive operation), and the duodenal switch (a malabsorptive operation). Information on these procedures can be found at: http://win.niddk.nih.gov/publications/gastric.h
